methanogenesis

Diversity of electron-bifurcating CO₂-fixing supercomplexes in methanogens
In the hydrogenotrophic methanogenic pathway, formylmethanofuran dehydrogenase (Fmd) reduces and fixes CO2, driven by low-potential …
Pablo San Segundo Acosta, Shunsuke Nomura, João Pedro Fernandes Queiroz, Evgenii Protasov, Jörg Kahnt, Masanori Kaneko, Georg Hochberg, Seigo Shima, Bonnie J. Murphy
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Biosynthesis of the [Fe]-hydrogenase cofactor
In the Shima group, we are interested in the enzymes involved in the biosynthesis of the FeGP cofactor. My project is focused in the catalytic mechanisms of the two radical-SAM enzymes involved in the first and last steps of the biosynthetic pathway.
[Fe]-Hydrogenase, Cofactor Biosynthesis and Engineering
[Fe]-hydrogenase catalyzes the heterolytic cleavage of H2 and reversible hydride transfer to methenyl-tetrahydromethanopterin. The …
Francisco J. Arriaza-Gallardo, Yu-Cong Zheng, Manuel Gehl, Shunsuke Nomura, João Pedro Fernandes Queiroz, Seigo Shima
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